4 edition of Disturbance Index Method for Assessing Severity of Procedures on Rodents (Ufaw Animal Welfare Research Report) found in the catalog.
Disturbance Index Method for Assessing Severity of Procedures on Rodents (Ufaw Animal Welfare Research Report)
W. J. Herbert
by Hyperion Books
Written in English
|The Physical Object|
|Number of Pages||36|
of rodents. We also provide references for testing details. Most of the behavioral meth-odology comes from research on rats, but the ethograms of rodents are similar enough to allow for generalization of the methods, if not many aspects of behavior, to other spe-cies. The testing method can be conceive of as having a number of stages, sequentially. This report, published on in November , is a major innovative piece of work carried out by the former Animal Procedures Committee that considers how .
Secure the hindquarters by pinning the tail against the palm with the fourth finger, or by allowing the hind limbs to rest on a solid surface. Figure 1: One-handed and two-handed restraint method for mice. There are a variety of gloves available for handlers to wear for protection from rat bites. They are generally unsuitable for work with mice. As a result of the second workshop, the document on “Definition of Criteria for Severity Assessment of Genetically Altered Laboratory Animals” was revised as well as the accompanying four forms for assessing genetically altered mice and rats. The documents are presented as Version 2 of 21 July Revisions are highlighted in Size: KB.
Guidance on the severity classification of scientific procedures involving fish: report of a Working Group appointed by the Norwegian Consensus-Platform for the Replacement, Reduction and. Guidelines for Assessment of Bone Microstructure in Rodents Using Micro–Computed Tomography Mary L Bouxsein, 1Stephen K Boyd,2 Blaine A Christiansen, Robert E Guldberg,3 Karl J Jepsen,4 and Ralph Mu¨ller5 1Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA 2Department of Mechanical Engineering, Schulich School of.
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Get this from a library. The disturbance index: a behavioural method of assessing the severity of common laboratory procedures on rodents. [R J Barclay; W J Herbert; Trevor B Poole]. A third method used to compare different experimental procedures or experiments is the “disturbance index,” a behavioral method for assessing the severity of procedures on rodents.
In this method, the degree of disturbance of a rodent's exploratory behavior caused by subjecting it to an experimental procedure is by: 8. Book review Full text access Disturbance index method for assessing severity of procedures on rodents: R. Barclay, W. Herbert and T. Poole, Universities Federation for Animal Welfare.
/sP (incl. postage and packing) (35 pages) ISBN 09 Hendriksen, C., W. de Leeuw. Production of monoclonal antibodies by the ascites method in laboratory animals. Res Immunol – PAIN is the official journal of the International Association for the Study of Pain and publishes original research on the nature, mechanisms and treatment of pain.
The journal provides a forum for the dissemination of research in the basic and clinical sciences of multidisciplinary interest. Topics include research on pain management and pain treatment.
PDF | On Apr 1,V. Baumans and others published Pain and distress in laboratory rodents and lagomorphs: Report of the Federation of European Laboratory Animal Science Associations (FELASA.
2 Each example relates to a hypothetical, but realistic, situation. It would not be appropriate to include all the detail that would be available in practice, but sufficient details are included to explain how the process was applied. As stated in the Working Document, it is essential to think through and tailor severity assessment to the species, strain andFile Size: KB.
Introduction. Mouse models have emerged as the tool of choice for basic research into obesity pathogenesis for a variety of reasons. Many key humoral signals (e.g., leptin, ghrelin) and neuronal circuits (e.g., the melanocortin system) involved in energy homeostasis were originally discovered and characterized in mice and subsequently were proven to be critical in humans as well Cited by: Necropsy and Sampling Procedures in Rodents Article (PDF Available) in Methods in molecular biology (Clifton, N.J.) September with 9, Reads How we measure 'reads'.
The disturbance index: a behavioural method of assessing the severity of common laboratory procedures on rodents. Universities Federation for Animal Welfare, Potters Bar, UK Google Scholar Baumans V. Environmental enrichment: practical by: The Disturbance Index: A Behavioral Method for Assessing the Severity of Common Laboratory Procedures on Rodents.
Hertfordshire, UK: Universities Federation for. Each year, an estimated million animals are used in scientific research activities around the many countries have guidelines that classify scientific procedures involving animals into categories of severity according to how they impact an animal’s welfare, these categorizations are often based on subjective evaluations instead of objective and reproducible assessments.
Review. Stroke is a common and permanent cause of disability that is associated with sensory and motor deficits including lack of coordination and partial paralysis [1,2].Additionally, higher cortical brain areas can be affected, and as a result, memory disturbances and other cognitive deficits often occur .Due to the devastating impairments an individual can encounter after suffering a Cited by: By J ohn C alder & G wen C hessell.
Wolfe Medical Publications, London. £ ISBN: 0 6. Reducing the Risk of Alzheimers. By M ichael A. W einer. Gateway Books, Bath. £ ISBN: 0 53 7. Disturbance Index Method for Assessing Severity of.
The mean daily chromodacryorrhoea score increased most with the severe disturbance of building maintenance work (F1,9 =p Cited by: The EWG for the assessment of severity met twice: in December with the focus on genetically altered animals, and in May discussing a general framework for assessing the actual severity experienced by animals in procedures.
This document is the result of the work of the two EWG meetings, discussions with theFile Size: KB. ABSTRACT. This essay discusses three potential models relating disturbance severity to post-disturbance stand composition in the boreal forest: (1) continuous, where changes in disturbance severity cause a proportional and continuous change in stand composition; (2) discontinuous, where a threshold disturbance severity exists beyond which major changes in composition occur; and (3) the cusp Cited by: supply of rodents does not exceed demand.
Rather, it should be used in conjunction with a number of reports including the LASA Task Force report4, and the more recent APC report5, in identifying good practices in assessing, evaluating and auditing breeding programmes for both conventional and genetically-altered stocks of rodents.
Key elements. Standards for Assessing the Quality of Laboratory Rodents. Laboratory animals are essential for conducting biomedical research world-wide. As most animals used for biomedical research are mice and rats, the quality of laboratory rodents has a major influence on.
Method Statement Arrive at site wearing correct PPE – high-viz vest, steel toe cap boots, hard hat and nitrile gloves, and sign in at office Use site plan to locate bait boxes While carrying out site inspection remain vigilant for signs of non-target speciesFile Size: 78KB.
Exotic zoology / Author: illustrated by Olga Ley. --Publication info: New York: Viking Press, Format: Book.Scoring the body condition of rodents is a noninvasive method for assessing health and establishing endpoints for adults where body weight is not a viable monitoring tool, such as with tumor models, ascites production, and pregnancy, or for young growing animals.
Body condition scores (BCS) range from 1 (emaciation) to 5 (obesity). In applied behavior analysis, thorough and quality assessments are important. It isn’t good enough to simply go through a quick survey, checklist, or interview questionnaire.